Universit� de Gen�ve

Neuroscience center

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Group leader: Fabienne Perren

Group name: Laboratory of ultrafast Ultrasound Neuroimaging in Clinics

Affiliation: University hospital

Research activities:

image Our projects, based on ultrafast ultrasound, a revolutionary noninvasive imaging tool, are dealing with its methodological developments in neurology and in particular in cerebrovascular diseases. They are intended to assess biomechanical properties of the cerebral vessels in various pathologies (aneurysm, vasculitis, atheromatosis), microcirculation (functional imaging), cerebrovascular blood flow and perfusion (modification, regulation) in ischemia (stroke, vasospasm) and in intracranial hyper- or hypotension.

Selected Publications:

  • Perren F., Louilidi J., Poglia D., Landis T., Sztajzel R. Microbubble potentiated transcranial duplex ultrasound enhances IV thrombolysis in acute stroke. J Thromb Thrombolysis 2008 Apr;25(2):219-23.
  • Reymond P., Bohraus Y., Perren F., Lazeyras F., Stergiopulos N. Validation of a patient-specific 1-D model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H1173-82.
  • Demené C., Tiran E., Sieu LA, Bergel A, Gennisson JL, Pernot M., Deffieux T. Cohen I. Tanter M.4D microvascular imaging based on ultrafast Doppler tomography. Neuroimage 2016 Feb;127:472-83.

Laboratory of ultrafast Ultrasound Neuroimaging in Clinics (LUNIC)
Service de Neurologie Département des Neurosciences cliniques
Geneva University Hospital
Email: Fabienne (dot) Perren (at) hcuge (dot) ch