Université de Genève

Neuroscience center

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Group leader: Adrian Guggisberg

Group name: Imaging-assisted neurorehabilitation

Affiliation: University hospital

Research activities:

image Neurological and cognitive deficits are frequent and highly disabling. Intensive training and rehabilitation can lead to improvement, but the selection of efficient treatment strategies for the individual patient is often difficult because of insufficient knowledge about how the human brain can recover lost functions. We make use of recent advances in neuroimaging techniques to non-invasively assess the network organization of the brain and to optimize treatment of patients with brain lesions. In particular, we aim to: - characterize the changes in brain network organization induced by focal lesions or diffuse degeneration; - visualize the mechanisms underlying functional recovery; - identify prognostic factors; - assess the effect of novel treatment approaches that might improve recovery, such as transcranial stimulation, neuro-feedback, and others. Functional imaging and advanced signal analysis techniques are also used to investigate the mechanisms of human cognition and behavior such as: decision-making, introspection, and yawning.

Group website: http://www.medecine.unige.ch/recherche/schnider/recovery.php

Selected Publications:

  • Guggisberg AG, Dalal SS, Zumer JM, Wong DD, Dubovik S, Michel CM, Schnider A. Localization of cortico-peripheral coherence with electroencephalography. NeuroImage , 2011; 57:1348-1357.
  • Martino J, Honma SM, Findlay AM., Guggisberg AG, Kirsch HE, Berger MS, Nagarajan SS. Resting Functional Connectivity in Patients with Brain Tumors in Eloquent Areas, Ann Neurol , 2011; 69: 521-532.
  • Guggisberg AG, Honma SM, Findlay AM, Dalal SS, Kirsch HE, Berger MS, Nagarajan SS. Mapping functional connectivity in patients with brain lesions. Ann Neurol 2008; 63:193-203.

Contact:
Geneva University Hospital
Service de Rééducation
Beau-Séjour
Email: Adrian (dot) Guggisberg (at) hcuge (dot) ch